Essential Information

Name of product: Eropid 50mg film-coated tablets
Active ingredient: Sildenafil 50mg
Form: Film-coated tablet
Pack size: (2,4 and 8)
Suitable for: Men over 18 years old with erectile dysfunction
Please always read the Patient Information Leaflet before taking this medicine.

 

About Eropid

Eropid contains 50mg of sildenafil that treats erectile dysfunction (ED) in men aged 18 year and over. It is available as a pharmacy only medicine (P medicine), which means you can purchase it without a prescription, from a registered pharmacy, under the supervision of a pharmacist.

Sildenafil is a well-established drug that is tolerated well and helps to get and maintain an erection. This helps patients to fully engage in sexual intercourse, whilst also providing emotional benefits, including helping patients to regain their self-esteem, self-confidence and relationship satisfaction. It was also shown to improve depressive symptoms in patients with erectile dysfunction.

How to take Eropid?

Take one dose (single 50mg tablet) with a full glass of water approximately 1 hour before planning to have sexual intercourse or masturbate, with a maximum of one single dose per 24 hours. It can be taken with or without food, but best to avoid a high fat meal, as it can cause the medicine to take longer to begin its effect.

How does Eropid Work?

Eropid can start working within 30 minutes, but patients are still able to obtain an erection in response to sexual stimulation for up to 4 hours after taking the dose. Sexual arousal and stimulation (foreplay) is still required to achieve an erection.

For most patients, sildenafil will work on the first instance. However, for others it can take additional attempts to obtain maximum benefit. If after 8 separate occasions the patient is still suffering from erectile dysfunction, they should be advised to consult their doctor.

You should visit your doctor within 6 months of starting to take Eropid for a general health check-up and may continue using the product after a review, provided there’s no change in their health or medication circumstances.

Contraindications for taking Eropid:

Do not take Eropid if you have taken any medicines called nitrates or nitric oxide donors, (such as glyceryl trinitrate, isosorbide mononitrate, isosorbide dinitrate, for the relief of chest pain or heart failure or amyl nitrite also known as “poppers”, nicorandil or sodium nitroprusside), as the combination may lead to a dangerous fall in blood pressure; For the full list of contraindications please consult the Patient Information Leaflet.

Avoid consuming grapefruit or grapefruit juice, as it may increase drug levels in the blood.

Large amounts of alcohol should be avoided, as it can increase side effects of Eropid and can impact sexual function.

Possible Side Effects:

Patients may experience some normal side effects, which include:

  • Headache; advise the patient to drink plenty of water.

  • Facial flushing, nausea, indigestion, blocked nose; these should soon pass.

  • Feeling dizzy, visual changes such as blurred vision or colour distortion; affected patients should not drive, use tools or operate heavy machinery until reactions/vision returns back to normal.

For a full list of potential side effects please consult the Patient Information Leaflet.

You must NOT take Eropid if:

Exclusion criteria:

• Under 18s, as this medicine is not indicated for this patient group and those with issues relating to erectile dysfunction should be directed to their GP.

• Women, this medicine is only indicated for men aged 18 years of over. If a female is interested in the product for their male partner, it’s important to encourage their partner to visit the pharmacy (or doctor) for advice.

• Those who do not have ED, this medicine will not enhance men’s erections, sexual performance or help with problems such as premature ejaculation – such patients with the latter should be advised to speak with their GP for advice.

• Those who are allergic to sildenafil or any other ingredient in the medicine.

Patients with the following health problems must not use Eropid:

– Hypotension (<90/50 mmHg).

– Previously diagnosed mild, moderate or severe hepatic impairment.

– Previously diagnosed severe renal impairment.

– Anatomical deformities of the penis, such as angulation, cavernosal fibrosis or Peyronie’s disease.

– With sickle cell anaemia, multiple myeloma or leukaemia.

– Loss of vision in one eye because of non-arteric anterior optic neuropathy (NAION), regardless of any connection with PDE5i exposure.

– Inherited eye disease such as retinitis pigmentosa.

– Bleeding issues (e.g. haemophilia) or those that suffer from stomach ulcers.

– Rare hereditary issues of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption) – Due to lactose within the product.

With the following cardiovascular issues:

– Breathlessness or chest pains during light or moderate physical activity e.g. Walking briskly for 20 minutes or climbing two flights of stairs

– Patients who have been advised against sexual activity because of a cardiovascular problem

– Patients who have had a stroke or a myocardial infarction within the last six months

– Patients with increased susceptibility to vasodilators including those with left ventricular outflow obstruction (e.g. aortic stenosis), or those with a rare syndrome of multiple system atrophy manifesting as severely impaired autonomic control of blood pressure

Patients previously diagnosed with the following:

– Uncontrolled hypertension

– Hypotension

– Unstable angina

– Moderate to severe valvular disease

– Left ventricular dysfunction

– Hypertrophic obstructive and other cardiomyopathies

– Significant arrhythmias

– Severe cardiac failure

Such patients with the aforementioned health problems should be advised to consult with their GP before requesting the use of this product.

Interacting Medications:

Patients taking the following medications must not use Eropid: 

– Nitrates; isosorbide mononitrate/dinitrate and glyceryl trinitrate, Nitric oxide donors; nicorandil and ‘Poppers’; amyl nitrate – Affects the NO cGMP pathway which sildenafil potentiates the hypotensive effects of

– Guanylate cyclase stimulators e.g. Riociguat – may lead to symptomatic hypotension

– Ritonavir – A potent CYP3A4 inhibitor that increase sildenafil plasma concentrations

– Already taking another PDE5i

– Alpha blockers; Phenoxybenzamine, phentolamine, tolazoline, trazodone, alfuzosin, doxazosin, tamsulosin, prazosin, terazosin

– CYP3A4 inhibitors

– Antibiotics; erythromycin, clarithromycin, rifampicin

– Antifungals; itraconazole, ketoconazole

– Calcium channel blockers; diltiazem, verapamil

– H2 antagonists; cimetidine

– HIV-protease inhibitors; amprenavir, fosamprenavir, atazanavir, darunavir, indinavir, lopinavir, ritonavir, saquinavir, tipranavir

Should any of the following side effects occur, patients should be advised to stop taking Eropid and seek immediate medical attention:

– Chest pains. If these occur before, during or after intercourse get into a semi-sitting position and try to relax. Nitrates must NOT be used to treat chest pain.

– A persistent and sometimes painful erection that lasts for more than 4 hours.

– A sudden decrease in hearing or loss of vision.

– An allergic reaction – symptoms include: sudden wheeziness, difficulty breathing or dizziness, swelling of the face, eyelids, lips or throat, peeling and swelling of the skin, blistering of the mouth, genitals and around the eyes, fever.

– Seizure or fits.

– A full list can be found in the Summary of Product Characteristics.

If you take more than the recommended dose, you should go immediately to the nearest Accident and Emergency facility or your on-call GP.

Advice for all Men

Men affected with ED should consult their doctor within 6 months for a clinical review of potential underlying conditions or causes of their erectile dysfunction. Some possible lifestyle changes that could help to reduce or eliminate risk factors for erectile dysfunction are:

Losing weight, if the patient is overweight

• Healthy eating with a balanced diet

• Regular exercise – recommended at least 150 minutes of moderate aerobic activity (e.g. cycling or brisk walking) every week

• Reducing stress – can recommend mindfulness therapy or yoga

• Giving up smoking – recommend smoking cessation services

• Reducing alcohol intake to moderate levels – max 14 units per week

• Avoiding recreational drug use